Lens Opacity in ABCA4-Associated Stargardt Disease Patients in the ProgStar Study.

Of the 259 participants, 54% were women, 86% were Caucasian, and the median age of STGD1 symptom onset was 19 years.

At baseline, median age = 31 (interquartile range [IQR] = 21-44, range = 6-68) years; lens opacity prevalence = 14.3% (69/483) of study eyes.

Among the 354 eyes without lens opacity at baseline, 2-year incidence was 5.6%.

Older age was associated with incidence: adjOR for every decade older = 4.1 (95% CI = 1.8-9.1).