Association of accelerometer-monitored physical activity with incident cataract: epidemiological and genetic evidence.

The study ultimately enrolled 77,123 participants with a mean age of 55.67 ± 7.8 years.

Dose-response analyses revealed U-shaped associations for MPA and MVPA, with the lowest risk observed at moderate volumes.

For other intensities, engaging in ≥300 min/week of MPA was associated with reduced risk (HR = 0.78, 95% CI: 0.66-0.92), while no significant associations were observed for LPA or VPA alone.