The Influence of Chalazion History on Meibomian Gland Loss and DED.
Worse meibomian gland loss linked to lower tear production after chalazion
The Influence of Chalazion History on Meibomian Gland Loss and DED.
To investigate the impact of chalazion history on meibomian gland loss and dry eye disease (dry eye disease).
This study was a retrospective case-control study.
worse gland damage strongly tracked with less tear production
Significant differences were observed between the chalazion and nonchalazion groups in tear meniscus height, BUT, conjunctival redness index, and lipid layer thickness ( p < 0.05).
The MG loss subgroup indicated statistically significant differences from the non-MG loss subgroup in chalazion recurrence frequency, surgical history, tear meniscus height, BUT, conjunctival redness index, and lipid layer thickness ( p < 0.05).
All differential indicators demonstrated no collinearity (VIF ≤ 10, tolerance ≥ 0.1).
Retrospective analysis revealed that a proportion of patients with meibomian gland loss had prior chalazion history, demonstrating distinct ocular surface characteristics compared to nonchalazion patients.
Recurrent chalazion episodes and surgical history were identified as significant contributors to meibomian gland loss, with glandular loss severity showing strong correlations with dry eye disease clinical parameters.