Post

New research · Ophthalmology
Talanta · 3d
Animal / preclinicalTalanta · 2026

ASCA-SHAP dual screening of PMI-related corneal ATR-FTIR spectral bands under temperature-dependent variation.

Qiang Chen, Xuehong Qian, Erzhu Shao … Shixiong Deng
Read paper
OphthalmologyAnimal / preclinical

Postmortem interval explained more corneal spectral variation than temperature did.

ASCA-SHAP dual screening of PMI-related corneal ATR-FTIR spectral bands under temperature-dependent variation.

Qiang Chen … Shixiong Deng
Talanta · 2026
Background

The estimation of postmortem interval (postmortem interval) is a long-standing scientific challenge in forensic pathology, and its accuracy is susceptible to environmental conditions.

Results

postmortem time explained the biggest share of corneal changes

27.38%
PMI
5.94%
Temperature
21.57%
PMI × Temperature
More results

Therefore, the relationship between postmortem interval and spectral features may change with temperature conditions.

The higher interaction effect suggests that temperature does not merely introduce constant background differences but also alters the spectral evolution trajectory related to postmortem interval.

More results

Through this screening framework, 56 wave numbers were identified and merged into 9 consecutive candidate spectral bands.

However, they should not be interpreted as completely independent biomarkers that are completely unaffected by temperature.

“
Conclusion

The proposed ASCA-SHAP dual screening framework in this study can provide candidate spectral features for cross-temperature and interpretable corneal postmortem interval models.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
AI / Informatics
0·962 for OCT
MerMED-FM was very accurate at diagnosing diseases using eye scans
AI / Informatics
0.98
Artificial intelligence's eyelid-height measurements matched doctors' manual measurements almost perfectly
AI / Informatics
92.1%
combining eye scans and photos correctly told benign from cancerous lesions apart nearly every time
Cohort Study
28.6%
recurred locally in more than 1 in 4 patients over years of follow-up
Cohort Study
-0.395
excision group's post-op eyelid fullness score was lower - greater improvement
Cohort Study
86.7%
of infants probed after 12 months still had unresolved tear duct blockage
Observational
16%
eyelid tissue in rosacea patients showed less of this key repair-signaling protein inside cell nuclei
Cohort Study
25%
about 1 in 4 treated cases had symptoms return after improving