ASCA-SHAP dual screening of PMI-related corneal ATR-FTIR spectral bands under temperature-dependent variation. | ScholarDeck

Paper

ASCA-SHAP dual screening of PMI-related corneal ATR-FTIR spectral bands under temperature-dependent variation.

New research · Ophthalmology

Talanta · 1mo

Animal / preclinicalTalanta· Jul 2026

ASCA-SHAP dual screening of PMI-related corneal ATR-FTIR spectral bands under temperature-dependent variation.

Qiang Chen, Xuehong Qian, Erzhu Shao … Shixiong Deng

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CorneaAnimal / preclinicalQ1IF 7.2

Postmortem interval explained more corneal spectral variation than temperature did.

ASCA-SHAP dual screening of PMI-related corneal ATR-FTIR spectral bands under temperature-dependent variation.

Qiang Chen … Shixiong Deng

Talanta · Jul 2026

Background

The estimation of postmortem interval (postmortem interval) is a long-standing scientific challenge in forensic pathology, and its accuracy is susceptible to environmental conditions.

Results

postmortem time explained the biggest share of corneal changes

27.38%

PMI

5.94%

Temperature

21.57%

PMI × Temperature

More results

Therefore, the relationship between postmortem interval and spectral features may change with temperature conditions.

The higher interaction effect suggests that temperature does not merely introduce constant background differences but also alters the spectral evolution trajectory related to postmortem interval.

More results

Through this screening framework, 56 wave numbers were identified and merged into 9 consecutive candidate spectral bands.

However, they should not be interpreted as completely independent biomarkers that are completely unaffected by temperature.

“

Conclusion

The proposed ASCA-SHAP dual screening framework in this study can provide candidate spectral features for cross-temperature and interpretable corneal postmortem interval models.

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