Post

New research · Ophthalmology
Current eye research · 3d
Cohort studyCurrent eye research · 2026

The Quest to Predict Surgically Induced Astigmatism After Cataract Surgery: Lessons for Toric IOL Planning.

Amanda C Pan, Klemens P Kaiser, Stefan Raidl … Jascha A Wendelstein
Read paper
OphthalmologyCohort study

Linear regression best predicted post-cataract corneal power changes, beating machine learning models.

The Quest to Predict Surgically Induced Astigmatism After Cataract Surgery: Lessons for Toric IOL Planning.

Amanda C Pan … Jascha A Wendelstein
Current eye research · 2026
Purpose

This study compared traditional statistical models with machine learning algorithms for predicting surgically induced astigmatism after cataract surgery, aiming to identify the most accurate and generalizable method among linear regression, regression trees, random forests, and neural networks.

Methods

Retrospective analysis was performed on 321 eyes (321 patients) undergoing phacoemulsification at a tertiary center.

n = 321 eyes
0.043
Results
0.043
linear regression's prediction error for corneal power change - lower is more accurate
n = 321 eyes
More results

Tree-based models performed slightly worse, while neural networks showed substantial overfitting with markedly higher test errors.

Preoperative astigmatism and corneal radii were the strongest predictors.

“
Conclusion · 1 of 3

KAST0 and KAST45 were not predictably modeled, whereas changes in KEQ.post were.

Conclusion · 2 of 3

Multivariable linear regression provided the most accurate and reliable predictions, while more complex machine-learning models (especially neural networks) overfit the limited dataset and offered no clinical advantage.

Conclusion · 3 of 3

The relationship between preoperative biometrics and postoperative equivalent power appears predominantly linear, though larger datasets may enhance machine-learning performance.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment