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New research · Ophthalmology
Journal of ophthalmology · 3d
Cross-sectionalJournal of ophthalmology · 2026

Evaluation of Macular Thickness, Choroidal Thickness, and Choroidal Vascularity Index in Women With Polycystic Ovary Syndrome: A Cross-Sectional Study.

Alper Güneş, Selim Gülücü
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OphthalmologyCross-sectional

Choroidal vascularity index higher in women with polycystic ovary syndrome

Evaluation of Macular Thickness, Choroidal Thickness, and Choroidal Vascularity Index in Women With Polycystic Ovary Syndrome: A Cross-Sectional Study.

Alper Güneş, Selim Gülücü
Journal of ophthalmology · 2026
Purpose

To evaluate macular thickness, choroidal thickness, and choroidal vascularity index (choroidal vascularity index) in women with polycystic ovary syndrome (polycystic ovary syndrome), and to assess the possible relationship between these parameters and sex hormone levels.

Methods

This cross-sectional study included 41 women with polycystic ovary syndrome and 46 age-matched healthy controls.

n = 41 women
Results

choroidal vascularity was much higher in polycystic ovary syndrome

PCOS
0.108LA1500
Control
0.101LA1500
More results

Subfoveal and 1000 µm nasal choroidal thicknesses were significantly greater in the polycystic ovary syndrome group ( p = 0.048 and 0.035, respectively).

No significant difference was observed in retinal nerve fiber layer thickness.

More results

In the systemic profile, BMI, fasting glucose, triglycerides, total cholesterol, LDL cholesterol, TSH, and T4 were comparable between groups.

Polycystic ovary syndrome patients had significantly higher LH, LH/FSH ratio, total testosterone, DHEA-SO4, insulin, HOMA-IR levels, and lower HDL cholesterol levels.

“
Conclusion · 1 of 2

Polycystic ovary syndrome is associated with increased choroidal vascularity and selected choroidal thickness parameters.

Conclusion · 2 of 2

choroidal vascularity index may represent a potential imaging marker of subclinical choroidal vascular alterations in polycystic ovary syndrome.

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