Cold Extremities and Underweight as a Combined Risk Profile for Open-Angle Glaucoma: A Population-Based Cross-Sectional Study in Korea.

Using nationally representative data from the Korea National Health and Nutrition Examination Survey 2008-2012 ( n = 8135; controls 7418, open-angle glaucoma 717), participants aged ≥ 50 years with measured intraocular pressure within the normal range (5-21 mmHg) at the time of examination were classified into four groups: non-underweight without cold extremities (N-N, reference), cold extremities only (cold extremities only), underweight only (underweight only), and underweight with cold extremities (UW+CE).