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New research · Ophthalmology
Japanese journal of ophthalmology · 3d
Cross-sectionalJapanese journal of ophthalmology · 2026

Comparison of AIZE-EX and SITA-standard visual field measurements in patients with glaucoma.

Kiyoshi Kano, Hiroki Nomoto, Chota Matsumoto … Yasuaki Kuwayama
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OphthalmologyCross-sectional

AIZE-EX perimetry took under half the time of SITA-Standard for glaucoma visual fields.

Comparison of AIZE-EX and SITA-standard visual field measurements in patients with glaucoma.

Kiyoshi Kano … Yasuaki Kuwayama
Japanese journal of ophthalmology · 2026
Purpose

To compare visual field test results between the AIZE-EX strategy of the imo perimeter and Humphrey field analyzer (humphrey field analyzer) Swedish interactive threshold algorithm (swedish interactive threshold algorithm)-standard in glaucoma patients.

Methods

Prospective This study included 52 eyes of 26 patients with glaucoma.

n = 52 eyes
Results
7
min 39 s vs. 15 min 24 s
time it took to complete the eye test, cut by more than half
n = 52 eyes
More results

MD was -7.89 ± 6.86 dB for AIZE-EX and -8.24 ± 7.13 dB for SITA-Standard (bias: +0.35 dB; 95% LoA: -4.04 to +4.73 dB; p = 0.342).

Patter standard deviation was 8.52 ± 4.15 and 8.20 ± 4.72 dB, respectively (bias: +0.32 dB; 95% LoA: -2.94 to +3.58 dB; p = 0.190).

More results

Two one-sided tests confirmed equivalence for both MD (90% CI: -0.26 to +0.95 dB; p = 0.002) and patter standard deviation (90% CI: -0.09 to +0.72 dB; p < 0.001).

Proportional bias was absent for MD (p = 0.405) but present for patter standard deviation (p = 0.012).

“
Conclusion · 1 of 2

MD and patter standard deviation values were comparable between the AIZE-EX and SITA-Standard derived from 24-2 test points, demonstrating clinical equivalence.

Conclusion · 2 of 2

Test time was substantially shorter with the AIZE-EX despite a greater number of points, supporting its use in routine glaucoma follow-up.

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