Efficacy of PAUL Glaucoma Implant® for Refractory Uveitic Glaucoma.

Cohort studyOcular immunology and inflammation· Jul 2026

Efficacy of PAUL Glaucoma Implant® for Refractory Uveitic Glaucoma.

Samy Si Larbi, Bahram Bodaghi, Valérie Touitou … Agathe Vest

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GlaucomaCohort studyTreatmentQ2IF 1.7

Paul Glaucoma Implant markedly lowered eye pressure in refractory uveitic glaucoma at 2 years.

Efficacy of PAUL Glaucoma Implant® for Refractory Uveitic Glaucoma.

Samy Si Larbi … Agathe Vest

Ocular immunology and inflammation · Jul 2026 · Q2 in Ophthalmology

Purpose

Evaluate the mid-term efficacy and safety of Paul Glaucoma Implant (Paul Glaucoma Implant) in patients with refractory uveitic glaucoma (refractory uveitic glaucoma).

Methods

Aged 18 years or older with refractory uveitic glaucoma and uncontrolled intraocular pressure (IOP) who underwent Paul Glaucoma Implant implantation between November 2021 and January 2025 at a tertiary uveitis center were included.

n = 25 eyes

Results

eye pressure was much lower after surgery, easing strain on the eye

More results

Mean preoperative IOP was 25.5 ± 7.7 mmHg with 3.5 ± 1.1 medications.

Complete success decreased from 28% at 6 months to 12.5% at 24 months, while qualified success increased from 72% to 87.5%.

Visual field mean deviation remained stable (mean change -0.79 dB; p = 0.21).

More results

Surgical reintervention was required in 2 eyes (8%).

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Conclusion · 1 of 2

Paul Glaucoma Implant provided sustained IOP reduction with a favorable safety profile in a refractory uveitic glaucoma population.

Conclusion · 2 of 2

These findings support the Paul Glaucoma Implant as a valuable surgical option in UG, although larger multicenter comparative studies are needed.

Efficacy of PAUL Glaucoma Implant® for Refractory Uveitic Glaucoma.

Efficacy of PAUL Glaucoma Implant® for Refractory Uveitic Glaucoma.

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