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New research · Ophthalmology
Neurology international · 4d
ReviewNeurology international · 2026

Route-Specific Meningo-Ophthalmic and Orbitomeningeal Communications Relevant to Middle Meningeal Artery Embolization: A Systematic Review and Meta-Analysis.

Alejandro Bruna-Mejias, Loreto Paez-Allendes, Valentina Perez-Lira … Juan Sanchis-Gimeno
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OphthalmologyReview

Middle meningeal artery arising from the ophthalmic artery is rare, pooled analysis finds.

Route-Specific Meningo-Ophthalmic and Orbitomeningeal Communications Relevant to Middle Meningeal Artery Embolization: A Systematic Review and Meta-Analysis.

Alejandro Bruna-Mejias … Juan Sanchis-Gimeno
Neurology international · 2026
Background

Meningo-ophthalmic and orbitomeningeal arterial communications comprise route-specific relationships between the middle meningeal artery (middle meningeal artery) and the ophthalmic or orbital arterial system.

Purpose

This systematic review aimed to synthesize the prevalence and anatomical patterns of these communications, using quantitative pooling only where the anatomical definition and denominator were sufficiently coherent.

Methods

This systematic review and meta-analysis were conducted according to PRISMA 2020 principles and registered in PROSPERO (CRD420261361050).

n = 558 records
Results

arising from that artery is uncommon, seen in about 3 in 100 cases studied

prevalence 0.03 (95% CI 0.01 to 0.13)
null 0
0.01
0.13
CI excludes the null - significant
More results

Database searches identified 558 records.

Forty-five reports were sought for retrieval; 10 were not retrieved or were not available as assessable full-text reports after retrieval auditing.

After excluding the clinically selected chronic subdural hematoma subgroup, the estimate was 0.02 (95% CI 0.01 to 0.06; I 2 = 7.7%).

More results

The meningolacrimal/lacrimal-middle meningeal artery route yielded an exploratory pooled proportion of 0.45 (95% CI 0.09 to 0.86; I 2 = 95.9%), with substantial anatomical and methodological heterogeneity.

“
Conclusion · 1 of 2

The available evidence supports route-specific synthesis rather than a single global prevalence estimate.

Conclusion · 2 of 2

middle meningeal artery arising from the ophthalmic artery appears uncommon but procedurally important; however, this estimate should be interpreted as a route-specific estimate across eligible angiographic/anatomical series rather than as a universal anatomical prevalence.

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