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Cohort studyDiagnostics (Basel, Switzerland) · 2026

Diabetes Mellitus Prevalence by Uveitis Etiology at a Japanese Tertiary Center.

Kei Wakatsuki, Kinya Tsubota, Masaki Asakage … Yoshihiko Usui

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OphthalmologyCohort study

Male sex is linked to higher diabetes prevalence among uveitis patients

Diabetes Mellitus Prevalence by Uveitis Etiology at a Japanese Tertiary Center.

Kei Wakatsuki … Yoshihiko Usui

Diagnostics (Basel, Switzerland) · 2026

Background

Diabetes mellitus (diabetes mellitus) may influence susceptibility to ocular infection and inflammatory phenotypes; however, disease-specific diabetes mellitus prevalence across uveitis etiologies has not been well characterized.

Methods

We evaluated diabetes mellitus prevalence across major uveitis entities in a large single-center cohort and compared observed prevalence estimates with age-specific national estimates from Japan.

n = 4751 patients

Results

aPR 2.11

Diabetes was about twice as prevalent in men versus women with uveitis, after adjustment

n = 4751 patients

More results

For each entity, expected diabetes mellitus prevalence was based on the corresponding national age-stratum estimate according to the mean age category of that entity.

Observed and expected diabetes mellitus prevalence estimates were compared using Fisher's exact test.

Overall, 166 of 3163 patients (5.3%) had diabetes mellitus.

More results

Diabetes mellitus prevalence differed substantially by etiology, ranging from 18.0% in endophthalmitis to 1.8% in Behçet disease.

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Conclusion

Older age and male sex were the strongest independent correlates of diabetes mellitus prevalence.

Post

Diabetes Mellitus Prevalence by Uveitis Etiology at a Japanese Tertiary Center.

Male sex is linked to higher diabetes prevalence among uveitis patients

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