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New research · Ophthalmology
Frontiers in ophthalmology · 4d
Cohort studyFrontiers in ophthalmology · 2026

Postoperative complications after cataract surgery with and without concurrent minimally invasive glaucoma surgery in patients with primary open angle glaucoma: a comparative risk analysis.

Sinan Ersan, Abdullah Virk, Daniel Zhu … Karen M Allison
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OphthalmologyCohort study

Combined cataract-glaucoma surgery linked to higher risk of postoperative hyphema

Postoperative complications after cataract surgery with and without concurrent minimally invasive glaucoma surgery in patients with primary open angle glaucoma: a comparative risk analysis.

Sinan Ersan … Karen M Allison
Frontiers in ophthalmology · 2026
Background

Primary open-angle glaucoma (primary open-angle glaucoma) is the most common form of glaucoma and a leading cause of irreversible blindness worldwide.

Methods

This retrospective cohort study utilized the TriNetX US Collaborative Network to identify all adults (ages ≥18 years) with a diagnosis of primary open-angle glaucoma who underwent CE/IOL with or without concurrent minimally invasive glaucoma surgery between 2006 and 2026.

n = 998 patients
Results

eye bleeding after surgery was much more common with combined surgery

CE/IOL with MIGS
1.19%
CE/IOL alone
0.15%
More results

After propensity score matching, each routine cataract surgery cohort (with and without minimally invasive glaucoma surgery) comprised 7, 998 patients.

More results

Similar associations were observed among patients undergoing routine or complex CE/IOL combined with minimally invasive glaucoma surgery compared with those undergoing routine or complex CE/IOL alone with respect to hyphema, cystoid macular edema, and retinal detachment.

“
Conclusion

In this large retrospective cohort study, combined CE/IOL with minimally invasive glaucoma surgery was associated with a significantly increased risk of postoperative hyphema, while rates of cystoid macular edema, retinal detachment, and endophthalmitis remained comparable to CE/IOL alone.

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