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New research · Ophthalmology
Journal of cataract and refractive surgery · 4d
Meta-analysisJournal of cataract and refractive surgery · 2026

Risk factors for late intraocular lens dislocation: a systematic review and meta-analysis.

Natalia S Anisimova, Maxim V Ivanov, Lisa B Arbisser, Valery P Erichev
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OphthalmologyMeta-analysis

Zonular weakness shows the strongest link to late intraocular lens dislocation after cataract surgery

Risk factors for late intraocular lens dislocation: a systematic review and meta-analysis.

Natalia S Anisimova … Valery P Erichev
Journal of cataract and refractive surgery · 2026
Methods

A systematic review and meta-analysis were performed according to PRISMA.

Results

zonular weakness raises dislocation risk far more than other factors

OR by subgroup · 95% CI
null = 1
found for zonular weakness
8.04
ocular trauma
5.98
uveitis
5.73
pseudoexfoliation syndrome
5.72
Myopia
3.32
More results

Myopia (OR 3.32, 95% CI 1.38-7.97) and glaucoma (OR 2.60, 95% CI 1.46-4.60) showed moderate associations, whereas previous vitrectomy and male sex were not statistically significant.

“
Conclusion · 1 of 2

Late intraocular lens dislocation is most strongly associated with structural and inflammatory damage to the capsular-zonular complex.

Conclusion · 2 of 2

High prevalence of a factor among cases does not necessarily indicate independent pathogenetic significance.

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