Predictive Performance of Hematological Parameters for Acute Respiratory Distress Syndrome in Hospitalized Pregnant and Postpartum Women With COVID-19.
Neutrophil-to-lymphocyte ratio is associated with predicting acute respiratory distress syndrome.
Predictive Performance of Hematological Parameters for Acute Respiratory Distress Syndrome in Hospitalized Pregnant and Postpartum Women With COVID-19.
Early identification of risk factors for acute respiratory distress syndrome (acute respiratory distress syndrome) in patients with coronavirus disease 2019 (COVID-19) is essential to guide preventive interventions.
This study aimed to evaluate the predictive performance of hematological parameters measured at hospital admission for acute respiratory distress syndrome in pregnant and postpartum women with COVID-19.
This retrospective cohort study included all pregnant and postpartum women hospitalized with COVID-19 between March 2020 and October 2021.
An AUC of 0.86 indicates good predictive performance for acute respiratory distress syndrome.
Overweight (37.8%) and obesity (45.9%) were the most frequent comorbidities.
Acute respiratory distress syndrome developed in 43.6% of patients, and 68.3% required invasive mechanical ventilation.
Patients with acute respiratory distress syndrome had significantly higher white blood cell and neutrophil counts and lower lymphocyte counts (all p < 0.001).
Both neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio were significantly associated with acute respiratory distress syndrome (p < 0.001).
Hematological parameters, particularly the neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio, measured at hospital admission may be useful for assessing the risk of acute respiratory distress syndrome in pregnant and postpartum women with COVID-19.
Further studies are needed to establish the predictive performance of these parameters for acute respiratory distress syndrome in this population.