Kahook Dual Blade: six-month results in uncontrolled open angle glaucoma.

Cohort studyInternational journal of ophthalmology· 2026

Kahook Dual Blade: six-month results in uncontrolled open angle glaucoma.

Susanna Friederike Koenig, Jens Ulrich Werner, Julie Charlotte Meyer … Armin Wolf

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GlaucomaCohort studyTreatmentQ2IF 1.8

Kahook Dual Blade surgery lowered eye pressure by 40.6% at 6 months in uncontrolled glaucoma.

Kahook Dual Blade: six-month results in uncontrolled open angle glaucoma.

Susanna Friederike Koenig … Armin Wolf

International journal of ophthalmology · 2026 · Q2 in Ophthalmology

Purpose

To investigate the intraocular pressure (IOP)-lowering efficacy of bleb-free ab interno trabeculectomy by means of the Kahook Dual Blade (Kahook Dual Blade).

Methods

This retrospective cohort study enrolled patients with uncontrolled open angle glaucoma (open angle glaucoma) who underwent standalone Kahook Dual Blade ab interno trabeculectomy.

n = 23 participants

40.6%

Results

40.6%

eye pressure dropped after surgery, well below the level that was uncontrolled before

n = 23 participants

More results

The baseline mean IOP was 21.7±5.6 mm Hg, with patients taking an average of 3.1±1.0 topical IOP-lowering medications, and 10 patients received adjuvant systemic acetazolamide preoperatively.

At the 3-month follow-up, the mean IOP decreased to 12.7±4.3 mm Hg, with a mean medication score of 2.9±1.8.

More results

Only mild postoperative hyphemata occurred in 10 cases, and no other surgery-related adverse complications were observed.

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Conclusion · 1 of 2

Standalone ab interno trabeculectomy with Kahook Dual Blade yields significant IOP reduction and favorable surgical safety in patients with uncontrolled open angle glaucoma, meanwhile decreasing the requirement of topical IOP-lowering medications.

Conclusion · 2 of 2

Long-term therapeutic efficacy remains to be further validated. Distinct from previous published studies, this study focuses on a Caucasian population and confirms surgical efficacy of Kahook Dual Blade as a single glaucoma procedure.

Kahook Dual Blade: six-month results in uncontrolled open angle glaucoma.

Kahook Dual Blade: six-month results in uncontrolled open angle glaucoma.

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