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New research · Ophthalmology
Ophthalmology · 5d
Cohort studyOphthalmology · 2025

Visual Outcomes after Strabismus Surgery in Pediatric Patients with Strabismic Amblyopia: An IRIS® Registry Study.

Mary Ellen Hoehn, Amin Nabavi, Amir Rahdar … Siamak Yousefi
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OphthalmologyCohort study

Vision improved substantially in amblyopic children by 24 months, whether or not they had strabismus surgery

Visual Outcomes after Strabismus Surgery in Pediatric Patients with Strabismic Amblyopia: An IRIS® Registry Study.

Mary Ellen Hoehn … Siamak Yousefi
Ophthalmology · 2025
Purpose

To evaluate the impact of strabismus surgery on visual outcomes in pediatric patients with strabismic amblyopia.

Methods

Pediatric patients 3 to 17 years of age with strabismus and amblyopia.

n = 1703 patients
Results

Average vision score improved from 0.46 to 0.29 logMAR at 24 months

Baseline
0.46logMAR
24 months
0.29logMAR
More results

Of the 21 242 patients analyzed, 1703 patients underwent surgery within 6 months of amblyopia diagnosis and 19 539 did not.

In the propensity score matching cohort, among patients with baseline visual acuity worse than 20/30, visual acuity significantly improved over time in both the strabismus surgery and no strabismus surgery groups.

More results

Improvement was most pronounced in the youngest group (3-7 years of age), whereas teenage patients (13-17 years of age) showed no improvement.

In multivariable logistic regression, no difference was found in the odds of treatment success, as measured by the IRIS-50, at the final follow-up between patients who underwent strabismus surgery and those who did not.

“
Conclusion · 1 of 2

Strabismus surgery did not impact visual outcomes significantly in patients with strabismic amblyopia. Older patients, up to at least 12 years of age, may still achieve visual benefits from both strabismus surgery and amblyopia treatment.

Conclusion · 2 of 2

FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

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