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New research · Ophthalmology
JAMA ophthalmology · 5d
AI / informaticsJAMA ophthalmology · 2025

Evaluation of AI Summaries on Interdisciplinary Understanding of Ophthalmology Notes.

Prashant D Tailor, Haley S D'Souza, Clara M Castillejo Becerra … John J Chen
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OphthalmologyAI / informatics

Most non-eye-specialist clinicians preferred notes with an AI-generated plain-language summary added.

Evaluation of AI Summaries on Interdisciplinary Understanding of Ophthalmology Notes.

Prashant D Tailor … John J Chen
JAMA ophthalmology · 2025
Background

IMPORTANCE: Specialized ophthalmology terminology limits comprehension for nonophthalmology clinicians and professionals, hindering interdisciplinary communication and patient care.

Purpose

To evaluate large language models-generated plain language summaries (plain language summaries) integrated into standard ophthalmology notes (standard ophthalmology notes) in improving diagnostic understanding, satisfaction, and clarity.

Methods

DESIGN, SETTING, AND PARTICIPANTS: Randomized quality improvement study conducted from February 1, 2024, to May 31, 2024, including data from inpatient and outpatient encounters in a single tertiary academic center.

n = 489
Results

most non-eye doctors preferred notes with the plain-language summary added

percentage point incre 9 (95% CI 0.30 to 18.20)
null 0
0.30
18.20
CI excludes the null - significant
More results

Plain language summaries semantic analysis found high meaning preservation (bidirectional encoder representations from transformers score mean F1 score: 0.85) with greater readability than standard ophthalmology notes (Flesch Reading Ease: 51.8 vs 43.6; Flesch-Kincaid Grade Level: 10.7 vs 11.9).

More results

Ophthalmologists (n = 489; 84% response rate) reported high plain language summaries accuracy (90% [320 of 355] a great deal) with minimal review time burden (94.9% [464 of 489] ≤1 minute).

Plain language summaries error rate on ophthalmologist review was 26% (126 of 489).

“
Conclusion · 1 of 2

In this study, use of large language models-generated plain language summaries was associated with enhanced comprehension and satisfaction among nonophthalmology clinicians and professionals, which might aid interdisciplinary communication.

Conclusion · 2 of 2

Careful implementation and safety monitoring are recommended for clinical integration given the persistence of errors despite physician review.

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