Post

New research · Ophthalmology
Journal of personalized medicine · 5d
Cohort studyJournal of personalized medicine · 2026

Layer-Specific Retinal Perfusion as a Personalized Biomarker: Evaluating the Subclinical Microanatomical Effects of Intracameral Cefuroxime After Routine Cataract Surgery.

Chia-Yu Wang, Chun-Yao Cheng, Yi-Jie Peng
Read paper
OphthalmologyCohort study

Intracameral cefuroxime linked to slower shrinkage of a key retinal capillary zone after cataract surgery

Layer-Specific Retinal Perfusion as a Personalized Biomarker: Evaluating the Subclinical Microanatomical Effects of Intracameral Cefuroxime After Routine Cataract Surgery.

Chia-Yu Wang … Yi-Jie Peng
Journal of personalized medicine · 2026
Background

The objective of this study was to evaluate macular perfusion changes after intracameral injection (injection) of cefuroxime at the end of phacoemulsification.

Methods

Who underwent routine phacoemulsification were enrolled.

n = 33 eyes
Results

capillary-free zone at fovea shrank less with cefuroxime - a milder change

Case (T10)
-0.06mm2
Control (T10)
-0.18mm2
More results

At T90, there was no statistically significant difference in the foveal avascular zone change in the deep capillary plexus between the groups.

More results

The postoperative changes in the vessel density, skeleton density, and acircularity index of the foveal avascular zone in the superficial capillary plexus and deep capillary plexus, central retinal thickness, and best-corrected visual acuity were similar between the groups in all 3 months.

“
Conclusion

Our findings indicate that intraoperative injection low-dose cefuroxime is associated with a temporary deceleration in foveal avascular zone reduction in the deep capillary plexus during the first postoperative month.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment