Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery.
With lomefloxacin, positive bacterial cultures fell to 48.3% by day 14.
Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery.
To evaluate the efficacy of topical lomefloxacin 0.3% versus chloramphenicol 0.2% with polymyxin B 2500 U/ml in the treatment of patients after strabismus surgery.
Seventy-nine consecutive patients who underwent strabismus surgery from April through October 2006 were randomized to receive topical lomefloxacin 0.3% (n = 45, 58 eyes) or chloramphenicol 0.2% with polymyxin B 2500 U/ml (n = 34, 40 eyes) postoperatively, in addition to topical dexamethasone 0.1% and diclophenac 0.1%.
fewer eye-swab tests found bacteria by day 14
From postoperative day 1 to day 28, rates of chemosis decreased from 96% to 9.5% in the lomefloxacin group and from 94% to zero in the chloramphenicol group; rates of hyperemia decreased from 100% to zero in both groups.
Accordingly, rates of a cumulative clinical sign score (clinical sign score) decreased from 60% to zero in the lomefloxacin group and 50% to zero in the chloramphenicol group.
Topical lomefloxacin is a potent alternative to topical chloramphenicol eye drops after strabismus surgery for the control of pain, infection and discharge, chemosis, hyperemia, and conjunctival hemorrhage.