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New research · Ophthalmology
Investigative ophthalmology & visual science · 6d
Cohort studyInvestigative ophthalmology & visual science · 2025

Glaucoma in Older Asians Aged 60 to 100 Years: Prevalence, Factors, Trends, and Projections (2024-2040).

Preeti Gupta, Sahil Thakur, Chiew Meng Johnny Wong … Ecosse L Lamoureux
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OphthalmologyCohort study

Glaucoma cases among older Singaporeans are projected to increase by 43% by 2040.

Glaucoma in Older Asians Aged 60 to 100 Years: Prevalence, Factors, Trends, and Projections (2024-2040).

Preeti Gupta … Ecosse L Lamoureux
Investigative ophthalmology & visual science · 2025
Purpose

To determine the prevalence, factors, temporal trends, and projections of glaucoma over 15 years among multiethnic older Asian adults aged 60 to 100 years.

Methods

We included 2380 participants (mean [SD] age, 73.6 [8.5] years; 55.2% female) from the baseline phase of the Population Health and Eye Disease Profile in Elderly Singaporeans (PIONEER; 2017-2022) study.

n = 2380 participants
43%
Results
43%
more older Singaporeans are expected to have glaucoma by 2040
n = 2380 participants
More results

The census-adjusted glaucoma prevalence was 5.1%, comprising 3.4% primary open-angle glaucoma, 0.7% primary angle-closure glaucoma, and 1% secondary glaucoma.

Prevalence was higher among Malays (6.5%) and Indians (6.2%) compared to Chinese (4.9%).

More results

Significant factors included older age (odds ratio [OR], 1.07), Malay ethnicity (OR, 2.07), higher intraocular pressure (OR, 1.14), longer axial length (OR, 1.20), cataract surgery (OR, 1.81), and polypharmacy (OR, 2.04).

“
Conclusion · 1 of 2

Glaucoma is common among older Singaporeans, with notable sociodemographic and modifiable clinical factors.

Conclusion · 2 of 2

Rising prevalence among Indians and the projected increase in cases underscore the need for targeted screening and early interventions.

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