Post

New research · Ophthalmology
NPJ digital medicine · 6d
StudyNPJ digital medicine · 2025

Re-identification of patients from imaging features extracted by foundation models.

Giacomo Nebbia, Sourav Kumar, Stephen Michael McNamara … Jayashree Kalpathy-Cramer
Read paper
OphthalmologyStudy

Foundation-model imaging features re-identified patients from 46.3% of optical coherence tomography images.

Re-identification of patients from imaging features extracted by foundation models.

Giacomo Nebbia … Jayashree Kalpathy-Cramer
NPJ digital medicine · 2025
Background

Foundation models for medical imaging are a prominent research topic, but risks associated with the imaging features they can capture have not been explored.

Purpose

We aimed to assess whether imaging features from foundation models enable patient re-identification and to relate re-identification to demographic features prediction.

Results

Optical Coherence Tomography eye scans could be matched back to the individual patient

40.3%
CFP
46.3%
OCT
25.9%
chest x-rays
More results

When training a deep learning model on the re-identification task, we reported performance of 82.3%, 93.9%, and 63.7% at image level on our internal Colour Fundus Photos, Optical Coherence Tomography, and chest x-ray data.

“
Conclusion

We showed that imaging features extracted from foundation models in ophthalmology and radiology include information that can lead to patient re-identification.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment