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New research · Ophthalmology
American journal of ophthalmology · 6d
GuidelineAmerican journal of ophthalmology · 2026

International Consensuses and Guidelines on Diagnosing and Managing Coats Disease by the Academia Retina Internationalis (ARI), the Asia-Pacific Vitreo-retina Society (APVRS), and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO).

Meenakshi Mahesh, Nishant V Radke, Rupesh Agrawal … Dennis S C Lam
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OphthalmologyGuideline

Experts reached consensus on 92.3% of Coats disease guideline statements.

International Consensuses and Guidelines on Diagnosing and Managing Coats Disease by the Academia Retina Internationalis (ARI), the Asia-Pacific Vitreo-retina Society (APVRS), and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO).

Meenakshi Mahesh … Dennis S C Lam
American journal of ophthalmology · 2026
Purpose

Coats disease is a rare, retinal vascular disorder characterized by telangiectasias, aneurysmal dilations, and progressive exudative retinal detachment.

Methods

Extensive literature search was done on multiple aspects of the disease-classification patterns, disease, Coats-plus, and Coats-like response.

92.3%
Results
92.3%
experts agreed on most guideline statements about Coats disease
More results

Most experts agreed on the suggested classification, diagnosis, and prognosis.

The controversy, however, remained in questions regarding association with other vascular disorders, treatment of stages 3 and 4, possible benefits of newer anti-vascular endothelial growth factor agents, and the role of artificial intelligence.

“
Conclusion · 1 of 2

These debates reflect the rarity of the condition, complex pathophysiology, and the challenges of treating a progressive blinding disease primarily affecting children.

Conclusion · 2 of 2

Hence, further studies are warranted, especially in areas that have not reached a consensus.

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