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New research · Ophthalmology
Antibiotics (Basel, Switzerland) · 1w
ReviewAntibiotics (Basel, Switzerland) · 2026

Current Recommendations, Antibiotic Resistance, and Emerging Treatments for Gram-Positive Ocular Infections in the United States.

Inès Fenniri, Camille André
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OphthalmologyReview

Nearly half of intraocular Staphylococcus aureus in United States surveillance was methicillin-resistant

Current Recommendations, Antibiotic Resistance, and Emerging Treatments for Gram-Positive Ocular Infections in the United States.

Inès Fenniri, Camille André
Antibiotics (Basel, Switzerland) · 2026
Background

Severe bacterial keratitis and endophthalmitis are leading causes of corneal scarring, enucleation, and permanent vision loss, and are increasingly complicated by multidrug-resistant Gram-positive ocular pathogens.

45.9%
Results
45.9%
Share of eye-infection Staphylococcus aureus samples resistant to methicillin-type antibiotics, 2009-2020
More results

While new antibiotics have been approved for systemic infections, vancomycin remains the standard of care for severe Gram-positive ocular infections.

“
Conclusion

Finally, this review discusses new drugs that represent promising alternatives to vancomycin in ophthalmology.

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