Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre…

Randomized trialBMJ (Clinical research ed.)· Oct 2023

Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial.

Sean Carrie, James O'Hara, Tony Fouweather … M Dawn Teare

Rhinology & SinusRandomized trialTreatmentQ1IF 3.0

Septoplasty improved nasal obstruction symptoms more than nasal sprays at six months

Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial.

Sean Carrie … M Dawn Teare

BMJ (Clinical research ed.) · Oct 2023 · Q1 in General Medicine

Purpose

To assess the clinical effectiveness of septoplasty.

Methods

378 adults (≥18 years, 67% men) newly referred with symptoms of nasal obstruction associated with septal deviation and at least moderate symptoms of nasal obstruction (score >30 on the Nasal Obstruction and Symptom Evaluation (Nasal Obstruction and Symptom Evaluation) scale).

n = 378 adults

Results

points lower score on a nasal symptom questionnaire with surgery than sprays

MD 20 (95% CI 16.40 to 23.60)

null 0

16.40

23.60

CI excludes the null - significant

More results

Greater improvement in SNOT-22 scores was predicted by higher baseline symptom severity scores.

Quality of life outcomes and nasal airflow measures (including peak nasal inspiratory flow and absolute inhalational nasal partitioning ratio) improved more in participants in the septoplasty group.

“

Conclusion

Septoplasty is a more effective intervention than a defined medical management regimen with a nasal steroid and saline spray in adults with nasal obstruction associated with a deviated nasal septum.

Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial.

Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial.

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