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Rita Ehrlich
Case reports in ophthalmology
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Case reportCase reports in ophthalmology · 2026

Anterior Chamber Sulfur Hexafluoride Injection for Hypotony Management: Case Report and Literature Review.

Malachy Nemet, Maya Kalev-Landoy, Rita Ehrlich, Liat Mendel-Veig
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OphthalmologyCase report

Anterior chamber sulfur hexafluoride injection rapidly increased eye pressure within 24 hours.

Anterior Chamber Sulfur Hexafluoride Injection for Hypotony Management: Case Report and Literature Review.

Malachy Nemet … Liat Mendel-Veig
Case reports in ophthalmology · 2026
Background

Hypotony is a potentially vision-threatening condition that may persist despite conservative management, often necessitating surgical or interventional treatment.

24
Results
24
h
Intraocular pressure rapidly increased within 24 hours after the sulfur hexafluoride injection.
More results

We present a case where a minimally invasive injection of 100% sulfur hexafluoride (SF6) into the anterior chamber (anterior chamber) successfully reversed refractory hypotony secondary to ciliary body shut-down.

More results

CASE PRESENTATION: A 72-year-old male with advanced pseudoexfoliation glaucoma and a nonfunctioning trabeculectomy presented with hypotony, decreased vision, a deep anterior chamber, and 360° serous choroidal effusions.

Given the refractory course, 100% SF6 gas was injected into the anterior chamber.

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Conclusion

This case highlights the potential of SF6 gas injection as a minimally invasive and effective treatment for refractory hypotony, even when the underlying mechanism is not over-filtration.

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