Anterior Chamber Sulfur Hexafluoride Injection for Hypotony Management: Case Report and Literature Review.
Malachy Nemet … Liat Mendel-Veig
Case reports in ophthalmology · 2026
Background
Hypotony is a potentially vision-threatening condition that may persist despite conservative management, often necessitating surgical or interventional treatment.
24
Results
24
h
Intraocular pressure rapidly increased within 24 hours after the sulfur hexafluoride injection.
More results
We present a case where a minimally invasive injection of 100% sulfur hexafluoride (SF6) into the anterior chamber (anterior chamber) successfully reversed refractory hypotony secondary to ciliary body shut-down.
More results
CASE PRESENTATION: A 72-year-old male with advanced pseudoexfoliation glaucoma and a nonfunctioning trabeculectomy presented with hypotony, decreased vision, a deep anterior chamber, and 360° serous choroidal effusions.
Given the refractory course, 100% SF6 gas was injected into the anterior chamber.
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Conclusion
This case highlights the potential of SF6 gas injection as a minimally invasive and effective treatment for refractory hypotony, even when the underlying mechanism is not over-filtration.