Sarcoidosis is associated with nearly one-fifth of uveitis cases in Hokkaido, Japan.
Epidemiological Characterization of Uveitis in Japan: a Systematic Review.
Tom Liba et al. · Ocular immunology and inflammation · 2025
Purpose
Study the etiologies, behind uveitis, examine the anatomical location, and explore how these causes vary across regions in Japan.
Methods
The systemic review was conducted followed the PRISMA guidelines, searching through databases, like PubMed/MEDLINE, Scopus, Central and Web of Science, from January 1990 to August 2024.
n = 1,738 studies
Results
Sarcoidosis is the most common systemic condition associated with uveitis in Hokkaido.
n = 1,738 studies
More results
Out of a total of 1,738 studies initially considered, only 20 met the criteria for inclusion.
Most studies showed a greater number of female patients.
In Tokyo, sarcoidosis accounts for 8.9% of uveitis cases, making it the most systemic association cause.
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Conclusion · 1 of 3
The findings reveal significant regional variations in the causes of uveitis across Japan, with sarcoidosis playing a major role.
Conclusion · 2 of 3
These regional differences underscore the importance of considering local factors in the diagnosis and treatment of uveitis.
Conclusion · 3 of 3
Additionally, the high prevalence of unclassified uveitis cases points to the urgent need for better methods to accurately identify and manage these conditions.