Lipid biomarkers of prostate cancer: insights from triglycerides and saturated fatty acid metabolism.

Case-controlFuture oncology (London, England)· Jul 2026

Lipid biomarkers of prostate cancer: insights from triglycerides and saturated fatty acid metabolism.

Jia Wei He, Pei Zhen Li

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Prostate CancerCase-controlDiagnosisQ1IF 2.6

Higher triglyceride levels associated with greater odds of prostate cancer

Lipid biomarkers of prostate cancer: insights from triglycerides and saturated fatty acid metabolism.

Jia Wei He, Pei Zhen Li

Future oncology (London, England) · Jul 2026 · Q1 in General Medicine

Background

Prostate cancer poses a substantial threat to men's health.

Methods

A multicenter case-control study was executed.

Results

Higher triglycerides linked to higher odds of prostate cancer

OR by subgroup · 95% CI

More results

Both indicators were positively correlated with continuous Gleason score (triglyceride: β = 0.710, OR = 2.89, 95% CI: 1.96-4.26, p < 0.001; saturated fatty acid/fatty acid: β = 0.645, OR = 2.57, 95% CI: 1.78-3.71, p < 0.001), and were significantly elevated in prostate cancer tissues compared with adjacent non-cancerous tissues.

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Conclusion

This study confirms the importance of triglycerides and saturated fatty acid/fatty acid ratio in prostate cancer progression, which could be used for diagnosis and prognosis. Reducing their levels may help prevent prostate cancer.

Lipid biomarkers of prostate cancer: insights from triglycerides and saturated fatty acid metabolism.

Lipid biomarkers of prostate cancer: insights from triglycerides and saturated fatty acid metabolism.

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