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New research · Ophthalmology
Ophthalmology · 22h
Cohort studyOphthalmology · 2026

Comparative Endophthalmitis Rates in Adult and Pediatric Patients across Various Ophthalmic Procedures: An IRIS® Registry Analysis.

Celine Chaaya, Eric A Goldberg, Connor J Ross … IRIS® Registry Analytic Center Consortium
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OphthalmologyCohort study

Open-globe repair is associated with the highest incidence of endophthalmitis in adult patients.

Comparative Endophthalmitis Rates in Adult and Pediatric Patients across Various Ophthalmic Procedures: An IRIS® Registry Analysis.

Celine Chaaya et al. · Ophthalmology · 2026
Purpose

To evaluate the incidence of endophthalmitis after ophthalmic surgery using a national ophthalmic registry.

Methods

In the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) who underwent ophthalmic surgeries were included in this analysis.

n = 17 457 881 procedures
0.94%
Results
Adults had the highest rate of eye infection after repairing a ruptured eye
n = 17 457 881 procedures
More results

The incidence of endophthalmitis was 0.097% (1 case per 1031 procedures) after vitrectomy for retinal detachment, 0.1% for trabeculectomy (1 case per 1000 procedures), 0.075% for tube shunts (1 case per 1333 procedures), and 0.068% for scleral buckle surgery (1 case per 1459 procedures).

More results

The incidence after cataract surgery was 0.038% (1 case per 2652 procedures), 0.039% (1 case per 2551 procedures) after standalone minimally invasive glaucoma surgery, 0.02% (1 case per 5013 procedures) after goniotomy, and 0.011% for strabismus surgery (1 case per 9091 procedures).

“
Conclusion · 1 of 3

Rates of endophthalmitis after ophthalmic surgical procedures are variable, with the highest incidence being open-globe repair. Minimally invasive glaucoma surgery procedures showed comparable infection rates as standard cataract surgery.

Conclusion · 2 of 3

A higher rate of infection after cataract surgery occurred in pediatric patients when compared with adults.

Conclusion · 3 of 3

FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

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