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New research · Ophthalmology
International ophthalmology · 22h
Cohort studyInternational ophthalmology · 2026

Clinical characteristics, management, and visual outcomes of presumed infectious and non-infectious anterior scleritis in a tuberculosis-endemic Indonesian Tertiary Center.

Muhammad Shafiq Advani, Beladina Maharani Putri, Made Susiyanti
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OphthalmologyCohort study

Non-infectious anterior scleritis was more common, affecting 58.3% of eyes.

Clinical characteristics, management, and visual outcomes of presumed infectious and non-infectious anterior scleritis in a tuberculosis-endemic Indonesian Tertiary Center.

Muhammad Shafiq Advani et al. · International ophthalmology · 2026
Purpose

To describe the demographic, clinical, and ocular characteristics of patients with presumed infectious and non-infectious anterior scleritis at a tertiary referral center in Indonesia and to compare management patterns and visual outcomes between the two groups.

Methods

We conducted a retrospective cohort study of patients diagnosed with scleritis between January 2019 and December 2023 at Department of Ophthalmology, Dr.

n = 96 eyes
58.3%
Results
more eyes had non-infectious inflammation of the eye's white outer layer
n = 96 eyes
More results

The mean age at presentation was 38.5 years, and most patients were female.

Nodular scleritis was more frequent in the presumed infectious group, whereas diffuse scleritis predominated in the non-infectious group.

“
Conclusion · 1 of 3

Non-infectious scleritis was more common than presumed infectious scleritis, although the proportion of presumed infectious disease was relatively high, likely due to the high proportion of presumed tuberculosis-associated cases.

Conclusion · 2 of 3

In tuberculosis-endemic settings, these findings underscore the need for careful etiologic evaluation, close follow-up, and multidisciplinary management.

Conclusion · 3 of 3

Interpretation remains limited by the retrospective design, incomplete follow-up, and limited microbiologic confirmation.

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