Prevalence, Incidence and Prognostic Impact of GLIM-Defined Malnutrition in Systemic Sclerosis: A…

Cohort studyClinical nutrition ESPEN· Jul 2026

Prevalence, Incidence and Prognostic Impact of GLIM-Defined Malnutrition in Systemic Sclerosis: A Longitudinal Cohort Study.

Bochao Jiang, Seyed Ehsan Saffari, Maria Noviani … Ennaliza Salazar

RheumatologyCohort studyPrognosisQ2IF 3.3

Malnutrition is associated with a higher mortality rate in patients with systemic sclerosis.

Prevalence, Incidence and Prognostic Impact of GLIM-Defined Malnutrition in Systemic Sclerosis: A Longitudinal Cohort Study.

Bochao Jiang … Ennaliza Salazar

Clinical nutrition ESPEN · Jul 2026

Background

Malnutrition is a known complication in systemic sclerosis (sclerosis), yet longitudinal data using standardised diagnostic criteria in Asian populations are limited.

Purpose

We aimed to determine the prevalence and incidence of malnutrition, identify risk factors for its development and evaluate its association with mortality in the sclerosis cohort using the Global Leadership Initiative on Malnutrition (GLIM) criteria.

Methods

Were included if they had at least one baseline assessment and ≥6 months of follow-up.

n = 341 patients

Results

malnutrition is associated with a higher rate of death in people with systemic sclerosis

HR by subgroup · 95% CI

More results

Among 341 patients with sclerosis, baseline malnutrition was 14.4%, with an incidence rate of 16.83 per 1000 person-years.

No baseline clinical variables were significantly associated with the development of malnutrition.

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Conclusion · 1 of 2

Despite a relatively low incidence, GLIM-defined malnutrition had a strong independent association with mortality in sclerosis.

Conclusion · 2 of 2

These findings are of prognostic value and support the integration of routine screening and standardized malnutrition diagnosis in sclerosis care in Asian populations.

Prevalence, Incidence and Prognostic Impact of GLIM-Defined Malnutrition in Systemic Sclerosis: A Longitudinal Cohort Study.

Prevalence, Incidence and Prognostic Impact of GLIM-Defined Malnutrition in Systemic Sclerosis: A Longitudinal Cohort Study.

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