Post

New research · Geriatrics
Annales d'endocrinologie · 1d
ReviewAnnales d'endocrinologie · 2026

Decision-making in primary hyperparathyroidism in older patients: surgical or conservative management?

Nathanaël Bassas Letissier, Evelyne Liuu, Gianluca Donatini … Helena Mosbah
Read paper
GeriatricsReview

Primary hyperparathyroidism affects 1.5% of adults over 65 years old.

Decision-making in primary hyperparathyroidism in older patients: surgical or conservative management?

Nathanaël Bassas Letissier et al. · Annales d'endocrinologie · 2026
1.5%
Results
the percentage of adults over 65 with overactive parathyroid glands
More results

While management is well codified before the age of 50, with surgery being preferred, recommendations for older individuals are less clear.

However, this indication must be weighed against the patient's co-morbidities, frailty and wishes.

Drug-based alternatives are a valid option for patients unable or unwilling to undergo surgery.

More results

The fundamental question, however, is to evaluate the suitability of one treatment over another, depending on the patient's phenotype.

“
Conclusion

The present article firstly describes the clinical and biological specificities of PHPT in older adults, secondly compares the therapeutic strategies available, and thirdly identifies geriatric markers to guide the therapeutic decision.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cohort Study
HR 2.52
the lowest nutritional risk index meant a higher risk of serious heart problems
Observational
12.42%
having Dental Prosthesis Laboratories increased the use of removable partial dentures among older adults
Guideline
“The guideline panel developed recommendations on caring for older adults during and after critical illness. Areas for future research were also identified during the guideline process.”
Cohort Study
HR = 1.31
higher general psychopathology brain scores are linked to a higher risk of death
Cohort Study
0.58
how well patients' own frailty ratings matched trained assessors' ratings
Cohort Study
41.2%
of older adults still had restricted mobility six months after their surgery
Study
8 questions
key research questions identified for lower leg soft-tissue injuries in older adults
Randomized Trial
mean difference 1.54
Average difference in goal attainment scores was 1.54, not statistically significant.