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New research · Hematology
Pediatric cardiology · 23h
Cohort studyPediatric cardiology · 2026

Comparative Analysis of Routine Blood Laboratory Tests in Multisystem Inflammatory Syndrome in Children (MIS-C) and Kawasaki Disease Among White and Black Children.

Namisha Khara, Luz A Padilla, Sabrina Chowdhury … Sadeep Shrestha
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HematologyCohort study

More low lab values linked to higher odds of Multisystem Inflammatory Syndrome in Children.

Comparative Analysis of Routine Blood Laboratory Tests in Multisystem Inflammatory Syndrome in Children (MIS-C) and Kawasaki Disease Among White and Black Children.

Namisha Khara et al. · Pediatric cardiology · 2026
Purpose

This retrospective study evaluated racial differences in age-adjusted laboratory parameters among children with complete Kawasaki Disease (KD) and Multisystem Inflammatory Syndrome in Children (MIS-C).

Methods

The cohort included 243 White KD, 249 Black KD, 43 White MIS-C, and 56 Black MIS-C patients.

OR 3.8
Results
Each additional low lab value associated with 3.8 times higher odds of Multisystem Inflammatory Syndrome in Children.
More results

Logistic regression assessed associations between cumulative laboratory abnormalities and MISC versus KD.

“
Conclusion

These findings suggest that MISC and KD are better differentiated by integrated, ageadjusted laboratory patterns of clinically meaningful laboratory abnormalities rather than absolute biomarker levels, supporting patternbased interpretation to improve clinical recognition and risk stratification across diverse pediatric populations.

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