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StudyBJS open · 2026

Cost-effectiveness of angiography-guided thyroidectomy to prevent postoperative hypoparathyroidism: Spanish National Health System model-based analysis.

Pablo Moreno-Llorente, Marta Ruiz, Arantxa García-Barrasa … Sebastián Videla

SurgeryStudy

Angiography-guided thyroidectomy offers €406.2 million in net monetary benefit.

Cost-effectiveness of angiography-guided thyroidectomy to prevent postoperative hypoparathyroidism: Spanish National Health System model-based analysis.

Pablo Moreno-Llorente et al. · BJS open · 2026

Background

Postoperative hypoparathyroidism is the most common complication after total thyroidectomy, and is associated with impaired quality of life and increased long-term healthcare use.

Methods

A model-based cost-effectiveness analysis was conducted comparing angiography-guided thyroidectomy with conventional thyroidectomy from the perspective of the Spanish National Health System.

€406.2 million

Results

This is the additional value angiography-guided thyroidectomy provides to the health system.

More results

Angiography-guided thyroidectomy was associated with lower lifetime healthcare costs (€563.7 million versus €613.2 million) and greater health benefits (310 997 versus 299 107 quality-adjusted life-years), yielding a gain of 11 889 quality-adjusted life-years and €49.5 million in cost savings.

More results

Scenario and joint probabilistic analyses confirmed robustness under alternative utility values and surgical outcomes.

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Conclusion · 1 of 2

Angiography-guided thyroidectomy may be a cost-saving innovation within publicly funded healthcare systems by reducing the incidence and chronic burden of postoperative hypoparathyroidism.

Conclusion · 2 of 2

These findings support broader adoption of fluorescence-guided surgery and underscore the need for real-world implementation studies to validate cost-effectiveness, and inform training and procurement strategies.

Cost-effectiveness of angiography-guided thyroidectomy to prevent postoperative hypoparathyroidism: Spanish National Health System model-based analysis.

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