Swarup S. Swaminathan - research works

A total of 790 eyes treated with SCS-TA were matched to 790 DEX-treated eyes and 790 control eyes.

The SCS-TA group received a mean of 0.6 additional SCS-TA injections and 1.0 total CS injections, compared with 1.0 DEX injections and 1.2 total CS injections in the DEX group.

IOP-lowering medication use increased in both CS groups during follow-up.

Glaucoma surgery occurred at crude 12-month rates of 2.0% for SCS-TA, 1.1% for DEX, and 1.4% for controls, with no significant differences between groups (SCS-TA: HR 1.33, 95% CI 0.62-2.86, P=0.469; DEX: HR 0.74, 95% CI 0.31-1.78, P=0.50).

F1 scores for glaucoma detection ranged from 95.4% to 98.9% across models.

For glaucoma type classification, accuracies were 97.1%, 94.2%, 94.2%, 94.0%, and 94.4% for Claude, DeepSeek, GPT, Grok, and Qwen, respectively.

F1 scores for the most prevalent type (POAG) ranged from 96.3% to 98.9%.

ICD-10 codes demonstrated substantially lower performance for type and severity staging, with overall accuracies of 89.2% and 58.5%, respectively.

The incidence of endophthalmitis was 0.097% (1 case per 1031 procedures) after vitrectomy for retinal detachment, 0.1% for trabeculectomy (1 case per 1000 procedures), 0.075% for tube shunts (1 case per 1333 procedures), and 0.068% for scleral buckle surgery (1 case per 1459 procedures).

The incidence after cataract surgery was 0.038% (1 case per 2652 procedures), 0.039% (1 case per 2551 procedures) after standalone minimally invasive glaucoma surgery, 0.02% (1 case per 5013 procedures) after goniotomy, and 0.011% for strabismus surgery (1 case per 9091 procedures).