S. Grace Prakalapakorn - research works

Six studies were rated level I, and 9 studies were rated level III.

Most level III evidence studies (5/9) reported outcomes using tacrolimus drops or ointment.

Apart from application site discomfort, the studies reported no significant adverse events.

All studies showed less myopic progression, with changes in spherical equivalent (SE) ranging from 0.22 to 0.81 diopters (D) for multifocal soft contact lenses compared with 0.50 to 1.45 D in control groups who used single-vision spectacles or single-vision contact lenses over the course of at least 1 year.

The difference in change between the groups was clinically modest and statistically significant in 11 studies for SE and in all 12 studies for AL.

No serious adverse events were reported in any of the studies.

All 33 articles (which reported results from 28 072 children) were rated level III.

Results from 28 072 children were reported, and most studies focused on children aged 6 years and younger.

Examination failure thresholds varied, but most studies after 2013 followed the 2013 American Association for Pediatric Ophthalmology and Strabismus (AAPOS) guidelines.

For the 21 studies that reported the referral rate (percentage of children who failed based on the screening result), the rate varied significantly (2.26%-63%).