Orly Gal‐Or - research works

Despite treatment with three intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections, the CNV demonstrated limited response and progressive enlargement, leading to poor final visual outcome.

All patients had ocular comorbidities, mainly glaucoma (n = 6) and pseudoexfoliation syndrome (n = 5).

Best corrected visual acuity improved from a median of 6/30 (0.7 logMAR) to a median of 6/12 (0.35 logMAR) (p = 0.06); postoperative astigmatism measured 0.91 ± 2.19 diopters.

UBM demonstrated well-balanced PCIOL fixation with no difference between the horizontal and vertical tilt measurements (p = 0.84; p = 0.94; p = 0.62; p = 0.085).

There was a high negative correlation between BCVA improvement and residual lens tilt (r = -0.76, p = 0.037).

The classification data set contained 330 images, and the localization data set included 659 images.

For GA localization, YOLOv8-Large achieved 91% sensitivity, 91% precision, IoU of 84%, and DICE coefficient of 88%.

Similarly, all macular measurements were significantly higher in the PCME eye compared to the contralateral eye (p < 0.001 for all).

In terms of RNFL measurements, the PCME eyes had greater global (p < 0.001), superonasal (p = 0.001) and superotemporal (p = 0.005) thickness values.

PCME eyes demonstrated a significant decrease in thickness for all macular and RNFL parameters following resolution of CME (p < 0.05 for all).

Mean age was 86.72 ± 7.18.

Third of the patients improved in ≥2 lines from presentation, all in the group of the pneumatic and TPA displacement.

Overall follow-up time was longer in the PPV group (median 4.9 vs 3.28 years, p = 0.005).

The hemorrhage was displaced in a similar percentage of patients in the tPA-and-gas group (n = 40, 78.4%) and the PPV group (n = 45, 80.4%) (p = 0.816).

Visual acuity (in LogMAR) was similar in the two groups prior to the diagnosis of subretinal hemorrhage but better in the tPA-and-gas group at the end of follow-up (p < 0.001).

She was diagnosed with macular detachment secondary to optic nerve head pit in her right eye and bilateral chorioretinal coloboma.

The cohort included 106 eyes of 102 patients.

No other complications related to the absence of prophylactic corneal sutures were encountered during surgery or follow-up.

The study included 68 eyes of 58 patients.

Among them, 24 eyes were treatment-naïve, and the remaining eyes had received a mean of 19.6 injections.

Immature lesions were more associated with treatment-naïve eyes and hyper-mature lesions were associated with previously treated eyes (p = 0.005).

Vascular density of the neovascular membrane was higher in the treatment-naïve group (p = 0.036) and the average MNV area was similar between the 2 groups (p = 0.683).

The most common indications for surgery in the NPDR group were ERM (67%) and rhegmatogenous retinal detachment (12.5%), while in the PDR group, indications were vitreous hemorrhage (56%) and tractional retinal detachment (19%).

There were no statistically significant differences in intra- and postoperative complication rates between the NPDR and PDR groups, even after adjusting for confounders; patient age at surgery and indication for surgery.

Overall, six consecutive patients (2 males, mean age 19.5 ± 9.74 years) were identified and studied.

Most common eye injuries included corneal erosion (n=4), traumatic hyphema (n=4), and retinal edema (n=3).

Mean initial logMAR visual acuity in the injured eye was 0.73 ± 0.18, improving to 0.25 ± 0.16 at the final visit (P = 0.125).

Two patients underwent eye surgery due to their trauma: one to repair globe penetration and another to undergo intravitreal injection of tissue plasminogen activator and C3F8 for submacular hemorrhage, followed 8 months later by intravitreal bevacizumab injection for choroidal neovascularization.

A total of 86 eyes of 85 consecutive patients, with mean age of 80.31 ± 8.06 and mean best-corrected visual acuity of 1.17 ± 0.58 logarithm of the minimal angle of resolution.

Two different subtypes of FTMHs were identified: tractional and degenerative.

Fifty (58%) degenerative FTMHs characterized with inverted trapezoid appearance and 36 (42%) tractional FTMHs characterized with hourglass appearance.

The presence of epiretinal membrane and pigment epithelium detachment where significantly higher in tractional FTMHs (P = 0.02, 0.03, respectively).

The experiment was repeated 45 times for each camera; 3 times for each of 3 mask types, on 5 volunteers, for a total of 90 trials.

Air leaks were detected with all investigated mask types.

The cohort included 30 patients, of whom 11 (36.7%) underwent intraoperative PFC injection.

Rates of macula-off RRD were similar in the two groups (54.5% and 47.4%, P = .705).

No association was found between PFC injection and metamorphopsia score.

Preoperative macula-off RRD was associated with significantly higher vertical and horizontal metamorphopsia scores than preoperative macula-on.

In the study group, staining for tPA was detected in the deep retinal layers in all eyes.

The staining was deeper and more intense at 3 and 24 h than at 48 h.

There was no tPA staining in the retina of eyes injected with saline.

The etiology of sustained ocular hypertension following intravitreal administration of anti-VEGF agents is yet to be unraveled.

Bevacizumab (25 mg/ml) was injected intravitreally after 3 days.

Donkey anti-human IgG labeled with Alexa Fluor(®) 488 was used for bevacizumab immunoreactivity detection.

Anti-CD31 antibody was used as a marker for Schlemm's canal endothelial cells.

Group A had a mean logarithm of the minimum angle of resolution VA of 0.63 ± 0.33 and 0.51 ± 0.31 preoperatively and 3 months after surgery, respectively.

Group B had a mean logarithm of the minimum angle of resolution VA of 0.47 ± 0.17 and 0.36 ± 0.17 preoperatively and 3 months after surgery, respectively.

No significant difference was found between the groups in change of VA.

The difference in macular thickness reduction between the groups was statistically significant.