Marissa K. Shoji - research works

Smoking was lowest in A ( p = .01).

Diplopia (46.4%, p = .001) and strabismus surgery (22.9%, p = .01) was most common in W.

B and H exhibited greater exophthalmos (B 22.8 ± 3.2 mm, H 22.1 ± 3.1 mm) than W and A (21.3 ± 3.6 mm, 21.0 ± 3.2 mm; p = .04).

Medial and inferior recti were largest in B and smallest in A ( p = .002, p = .05), with reciprocal FMR (highest in A, lowest in W).

A total of 215 cases were identified, extrapolating to 6466 US cases (95% CI, 3736-9195) over the last 20 years.

Of 215 patients, 169 were male (79%), 148 were pediatric (<18 years; 69%), and 178 had equipment-related trauma (83%).

Injury incidence was similar among ice (23 [11%]), field (21 [10%]), and street hockey (23 [11%]).

Pediatric patients had more minor anterior segment injuries (95 of 148) compared with adults (31 of 67; 64% vs 46%; difference, 18%; 95% CI, 3.8-31.9; P = .02), while adult patients had more major posterior segment injuries (4 of 67; 6% vs 0%; difference, 6%; 95% CI, 1.6-14.4; P = .009).

Thus, this study summarizes and evaluates the effectiveness and safety of ICIs for periocular MCC.

Non-human studies, non-periocular MCC, and reports without ICI treatment were excluded.

Extracted data included patient demographics, tumor characteristics, treatment regimen, and patient outcomes.

Treatment regimens consisted of pembrolizumab (n = 6) and avelumab (n = 3), or both medications (n = 1).