Lauren A. Dalvin - research works

Mean visual acuity declined from 0.34 logMAR (20/44) at diagnosis to 0.82 logMAR (20/132) at the last follow-up.

Among eyes beginning with ≥20/40, corresponding probabilities were 73%, 52%, 26%, and 8%.

Iodine 125 plaques (sHR [subdistribution hazard ratio]: 3.57 vs ruthenium 106; 95% CI: 2.43-5.23) independently predicted vision <20/200, while each additional millimetre of tumour-fovea distance was protective (sHR 0.90; 95% CI: 0.86-0.95).

Ten-year incidences of BCVA <20/200 were 24%, 49%, and 77% in low-, medium-, and high-risk FIT categories.

Among 31 eyes of 29 patients, 14 eyes had optic nerve invasion and 6 had choroidal invasion.

The predictive model for optic nerve (ON) invasion achieved Area under the receiver operating characteristic curve (AUROC) of 0.85 (accuracy 0.84, sensitivity 0.93, specificity 0.76) using the radiomic features of maximum 2D diameter slice on the unaffected optic nerve (ON), correlation of grey level co-occurrence matrix (GLCM) on the affected ON, and kurtosis of affected ON.

The study included 25 patients (median age 76.6 years).

Mean time from presentation-to-treatment was 5.67 months (range 0.26-28.52 months), with a subset experiencing prolonged delays.

Local tumor recurrence occurred in 4 (16%) at a median of 26.46 months.

Overall survival was 54.2% at 10 years, with no deaths attributed to sebaceous carcinoma.

Five-year Kaplan-Meier estimates of ocular AEs were 59.6% radiation maculopathy, 42.0% cystoid macular edema, 55.2% nonproliferative radiation retinopathy, 10.8% proliferative radiation retinopathy, and 35.6% radiation papillopathy.

The median age of the patients was 67 years (range 59-71), and the sex distribution was 72 females (54%) and 62 males (46%).

On OCT, 35 (26%) eyes showed RPE undulations, which were more common in Asians (61%) than in the American population (16%).

In addition, 67 (50%) eyes exhibited sub-RPE/subretinal hyperreflective lesions, and 45 (34%) eyes had intraretinal lesions.