Jie Li - research works

Compared with the IDON group, patients with CTD-ON showed significantly more severe visual impairment and worse prognosis (P < 0.05).

Optic nerve hyperintensity on DWI (DWI-H) was a significant risk factor for visual acuity at onset and final visual outcome in ON patients [ORs = 1.893 (95% CI: 1.322-2.711, P < 0.001), 1.716 (95% CI: 1.094-2.691, P = 0.019), respectively].

Acute CTD-ON patients were at higher risk of poor visual outcomes [OR = 2.593 (95% CI: 1.384-4.857, P = 0.003)].

Among the 156 basal-like breast carcinoma (BLBC) cases, ALK presented three distinct localization patterns: diffuse cytoplasmic granular, cytoplasmic/membranous, and cytoplasmic/nuclear.

ALK gene copy number abnormalities were detected in 16.8% of cases, with a higher prevalence in p53-mutant and high Ki67 expression tumors.

Notably, ALK protein positivity and gene copy number gain were associated with poorer survival outcomes, including 5-year overall survival (OS) and 10-year recurrence-free survival (RFS).

Secondary outcomes, including mortality, postoperative antibiotic duration, renal function parameters, and microbiological eradication rates, were similar between groups.

Independent predictors of postoperative sepsis included failure of microbiological eradication, higher baseline C-reactive protein, and larger stone burden.

Findings were consistent in sensitivity analyses.

Baseline characteristics were similar between groups (all p > 0.05).

Intraoperative blood loss was reduced (98.70±28.97 vs 155.00±65.76 mL, p < 0.001), but operative time was longer (249.7±19.7 vs 199.6±22.7 min, p < 0.001).

No significant differences were found in time to bowel function recovery or 90‑day complication rate.