Jeffrey D. Zampi - research works

The recommendation statements reflect contemporary expert opinion on the timing and decision-making for pulmonary valve replacement in children.

Necrotizing enterocolitis (NEC) is common in these infants, although specific risk factors have not been identified to predict those who will develop NEC.

Hypoplastic left heart syndrome accounted for 54.3% of patients.

Stage 1 NEC occurred in 42 infants (75.0%), with stage 2/3 NEC occurring in 14 infants (25.0%).

Having three or more risk factors leading to the decision to undergo HS1P was associated with development of NEC (p = 0.01).

Among 417 neonates, 180 (43%) underwent primary repair and 237 (57%) staged repair.

Most were prenatally diagnosed (59%), non-Hispanic White (63%), and publicly insured (54%).

Maternal race-ethnicity and public insurance were associated with longer hospital stays and increased in-hospital complications.

At 6 months, predicted probability of VA burden decreased below baseline for Harmony patients (-6%; 95% CI: -10% to -2%; P < 0.001) and to baseline for Alterra (P = 0.53).