Jae‐Joong Kim - research works

Although effective treatments, such as therapeutic plasma exchange, immunosuppressive therapy with rituximab, and caplacizumab, have significantly improved survival, important challenges remain.

These include limited diagnostic capacity, barriers to the early use of novel therapies, and long-term complications.

In Korea, additional difficulties persist due to the restricted availability of ADAMTS13 antibody testing, reimbursement limitations for rituximab, and the absence of caplacizumab in clinical practice.

Amyloid burden decreased substantially during follow-up.

Conversion to amyloid-negative status (full treatment-related amyloid clearance) occurred in 9 of 50 patients (18.0%) and was more frequent at the MCI stage ( p = 0.022).

Patients treated at the MCI stage also showed more favorable short-term cognitive and functional trajectories than those treated at the dementia stage.

This guideline summarizes evidence-based post-cardiac arrest care following the return of spontaneous circulation (ROSC) in adults, incorporating updates from the 2025 Korean Guidelines for Cardiopulmonary Resuscitation and contemporary international evidence.

After ROSC, early evaluation should focus on identifying reversible causes.

A 12-lead electrocardiogram should be obtained promptly, with echocardiography and whole-body computed tomography performed when clinically indicated to assess cardiac function and detect noncardiac or occult etiologies.

Hemodynamic management prioritizes adequate organ perfusion and prompt treatment of shock, including active correction of hypotension.