Hui Li - research works

Conventional endoscopic hemostasis has limited efficacy in preventing rebleeding, and surgical resection presents significant risks and is often not feasible.

In this study, we used EUS-VE for acute duodenal tumor-related bleeding.

Among the 12 patients, the 90-day rebleeding and mortality events occurred in 1 (8.33%) and 3 (25%) patients, respectively.

Three patients (25%) developed fever after EUS-VE, including one case suspected to be procedure-related.

Pre-existing bowel dysfunction was associated with a higher likelihood of developing AF ( p < 0.05).

Smoking, alcohol consumption, prolonged sedentary or standing occupations, and higher body mass index (BMI) were also associated with AF.

In exploratory analyses of AF subtypes, diarrhea showed modest heterogeneity across anatomical classifications, whereas constipation showed no significant variation across subtypes.

Overall, 1405 patients (74.6%) experienced at least one IV medication-related DRP, with treatment safety problems predominating.

Based on this model, a web-based clinical decision support tool was developed to provide individualized IV medication risk stratification at the point-of-care.

Five core indicators were identified: Modic Changes (MC), Basal Width Of The Herniated Disc (BWHD), Body Mass Index (BMI), Ratio Of Disc Herniation (RDH), and Interspinous Ligament Injury (ILI).

Risk thresholds for BWHD, BMI, and RDH were 1.7 mm, 23.3 kg/m², and 37.2%, respectively.

Laparoscopy-assisted LDLT was successfully performed in all 13 pediatric patients.

The mean total operative time was 478 min (range, 315-615 min), the median portal vein clamping time was 47 min (range, 33-107 min), the average time required to remove the liver was 229 min (range, 115-357 min), and the median cold ischemia time was 85 min (range, 29-214 min).

The intraoperative course for all the recipients was uneventful.

Unsupervised anomaly detection, which learns exclusively from normal cases to identify significant deviations from normative patterns without prior knowledge of specific anomaly types, offers a promising approach for automatic diagnosis of such conditions.

To enhance anomaly detection capabilities, this study introduces a three-dimensional (3D) Patch-based brain ANomaly Detection framework via Age prediction (PANDA), utilizing the maximum AAD across all patches (MaxAAD) as a biomarker for identifying fetal brain anomalies.

IGF2 signaling was elevated in myopic MG cells and correlated with ERK/Fos activation.

In vivo siIGF2 attenuated myopia progression, preserved retinal function/structure, suppressed MG activation/proliferation and GMT/ECM marker expression, and reduced inner limiting membrane abnormalities and retinal stiffening.

Conversely, in vitro, rhIGF2 activated the ERK/Fos pathway, promoting proliferation, migration, GMT-like response, and collagen synthesis in MIO-M1 cells.

These findings demonstrate that early myopia involves Fos⁺ MG-driven retinal remodeling via GMT-like response, coupling visual stress to ECM and mechanical changes.

All POP-Q indicators improved significantly at 3 months, 1 year, and 2 years compared with baseline (all P < 0.001).

PFDI-20 scores decreased from 144.6 ± 44.5 preoperatively to 52.1 ± 21.3 (3 months), 13.7 ± 11.1 (1 year), and 8.1 ± 8.5 (2 years) ( P < 0.001).

Overall postoperative SUI symptom rate was 3.7%.

POP recurrence occurred in 2.2%.

High‑AEN tumors exhibited a non‑inflamed TME, predicted immunotherapy resistance, yet increased chemosensitivity.

EZR was nominated as a causal driver; knockdown of EZR suppressed proliferation, migration, and tumor growth via YAP/TAZ dysregulation.