Gustav Stålhammar - research works

Mean visual acuity declined from 0.34 logMAR (20/44) at diagnosis to 0.82 logMAR (20/132) at the last follow-up.

Among eyes beginning with ≥20/40, corresponding probabilities were 73%, 52%, 26%, and 8%.

Iodine 125 plaques (sHR [subdistribution hazard ratio]: 3.57 vs ruthenium 106; 95% CI: 2.43-5.23) independently predicted vision <20/200, while each additional millimetre of tumour-fovea distance was protective (sHR 0.90; 95% CI: 0.86-0.95).

Ten-year incidences of BCVA <20/200 were 24%, 49%, and 77% in low-, medium-, and high-risk FIT categories.

Mel AI noma scores increased monotonically with higher MOLES categories ( p = 0.0001).

In univariable logistic regression, both MOLES and Mel AI noma scores were associated with increased odds of melanoma diagnosis.

In multivariable analysis including both scores, each remained independently associated with melanoma diagnosis.

In univariate analyses, both latitude and the G allele frequency were positively associated with OM incidence.

Mediation analysis indicated that about 92% of latitude's effect on incidence was mediated through G allele frequency.

In competing risk regression, it produced a higher Wald statistic (761 vs 628) and a subdistribution hazard ratio of 1.42 versus 1.22.

Cox regression for melanoma-related mortality demonstrated higher hazard ratios, peaking at 24 for the new model compared with 13 for the AJCC classification.

Cumulative incidence analyses revealed 15-year metastatic death rates ranging from 7% to 76% with the new system versus 11% to 69% with AJCC, widening the absolute range by 11 percentage points.