Brent Siesky - research works

IOP values obtained by DCT and GAT showed a strong positive correlation in patients with OAG (r=0.93; P<0.001).

Mean IOP measured with DCT [18.4 (5.1) mm Hg] was significantly higher (P<0.001) than GAT IOP measurements [16.5 (4.5) mmHg].

The Bland-Altman data showed that the amount of disagreement between IOP assessment techniques varied, suggesting a proportional bias.

Mean baseline IOP was 16.5 ± 3.4 mmHg.

Adjunctive dorzolamide therapy significantly decreased vascular resistance in the ophthalmic artery (p = 0.02).

Mean diastolic BP and OPP were significantly lower after adjunctive therapy.

There were no changes in retinal microcirculation between the two phases of treatment.

No statistically significant differences in visual field or nerve fiber layer thickness were observed between the treatment groups during 12 months of therapy.

Mean increase over 1 year of treatment in ocular perfusion and diastolic perfusion pressures were 10.46% and 10.67% in the DTFC group and 7.47% and 5.61% in the LTFC group, respectively.

OA resistive index (RI) and SPCA RI were significantly different at the 12 months visit between the two treatment groups (p=0.05 and p=0.000, respectively): DTFC treatment showed decrease in the RI.