Basil K. Williams - research works

Sixteen patients underwent biopsy using this technique for suspected small choroidal melanoma (1.5 mm average thickness).

Of 2 patients without yield, there was a technical processing error and an anteriorly located tumor.

No complications were observed.

A total of 375 patients (mean age 64 ± 14 years; 50.4% female) were treated with Iodine-125 plaque brachytherapy.

The incidence of sensory-deprivation related strabismus was 3.7% (14/375).

Those with worse baseline visual acuity and greater tumor distance from the optic disc had lower odds of diplopia (P = .005 and P = .026, respectively).

Superior rectus muscle manipulation (P = .010), younger age (P = .045), and moderate (P = .022) or severe (P = .045) vision loss were associated with increased odds of developing strabismus.

After propensity score matching with 615 983 patients undergoing cataract surgery, 7422 patients had a prior PPV.

After propensity score matching, among patients with prior PPV, mean (SD) age was 62.0 (11.6) years, and 3623 patients (49.5%) were female; among the non-PPV group, mean (SD) age was 61.9 (12.2) years, and 3625 patients (49.5%) were female.

Elevated CME risk persisted in subgroup analyses evaluating prior PPV for RD (5.65% vs 1.22%; absolute difference, 4.43%; 95% CI, 3.48%-5.38%; RR, 4.62; 95% CI, 3.20-6.67; P < .001), as well as those for non-RD indications (3.99% vs 1.23%; absolute difference, 2.76%; 95% CI, 2.06%-3.48%; RR, 3.26; 95% CI, 2.36-4.50; P < .001).

After PSM, primary enucleation within 90 days of diagnosis occurred in 5.2% of Black/Hispanic patients versus 3.8% of NHW patients (risk ratio [RR] 1.36, 95% confidence interval [CI] 0.821-2.253, p = 0.2305).

Cumulative rates of liver metastasis in the Black/Hispanic group were significantly higher than NHW at 1 year (RR 2.42, CI: 1.336-4.387), 3 years (RR 1.96, CI: 1.246-3.083), and 5 years (RR 1.77, CI: 1.195-2.611) ( p < 0.01 for each).

Eyes treated with PPV alone demonstrated a mean postoperative myopic shift of -0.05±0.53D compared with -1.03±0.78D in eyes that received SB as part of repair (p<0.05).

Patients receiving #240 bands demonstrated the smallest mean myopic shift (-0.78±0.62D) compared with #41 bands (-1.14±0.84D) and #42 bands (-2.0±0.71D), although differences were not statistically significant (p=0.07).