Long-term medical and psychosocial vulnerability after home return following severe traumatic brain injury.

Cohort studyJournal of rehabilitation medicine· Jul 2026

Long-term medical and psychosocial vulnerability after home return following severe traumatic brain injury.

Andrea Calderone, Carmela Rifici, Donatella Bonaiuti … Rocco Salvatore Calabrò

Read paper

Brain Injury MedicineCohort studyQ1IF 2.1

474 of 2,835 severe TBI survivors showed multidomain vulnerability at 5 years.

Long-term medical and psychosocial vulnerability after home return following severe traumatic brain injury.

Andrea Calderone … Rocco Salvatore Calabrò

Journal of rehabilitation medicine · Jul 2026 · Q1 in Rehabilitation

Purpose

To identify a 5-year medical and psychosocial vulnerability profile among adults living at home 1 year after severe TBI and examine associated early characteristics.

Methods

Retrospective secondary analysis of a multicentre longitudinal cohort.

n = 2,835 participants

474

Results

474

these survivors had worse mood, anxiety, life satisfaction, and rehospitalization across multiple domains

n = 2,835 participants

More results

The latter showed more depressive symptoms, anxiety symptoms, low life satisfaction, and rehospitalization, with poorer 5-year functioning, participation, health, productive status, and higher frequency of non-private residence.

More results

Better 1-year global outcome was protective; female sex, preinjury illicit drug use, and living alone at 1 year were associated with assignment to this profile.

“

Conclusion

Home return after severe traumatic brain injury should be treated as a transition point for longitudinal rehabilitation surveillance.

Long-term medical and psychosocial vulnerability after home return following severe traumatic brain injury.

Long-term medical and psychosocial vulnerability after home return following severe traumatic brain injury.

Related papers