Fever Burden and Neurological Outcome in Traumatic Spinal Cord Injury.

Cohort studyNeurotrauma reports· 2026

Fever Burden and Neurological Outcome in Traumatic Spinal Cord Injury.

Tommaso Rochat, David Legouis, De Stefano Pia, Quintard Hervé

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Spinal Cord Injury RehabilitationCohort studyPrognosisQ3IF 1.9

Greater fever burden is associated with poorer neurological recovery after traumatic spinal cord injury.

Fever Burden and Neurological Outcome in Traumatic Spinal Cord Injury.

Tommaso Rochat … Quintard Hervé

Neurotrauma reports · 2026

Background

Fever is a frequent complication after traumatic spinal cord injury (traumatic spinal cord injury) and may exacerbate secondary neurological damage through increased metabolic demand, inflammation, and impaired perfusion.

Methods

We conducted a retrospective observational study of adults with acute traumatic spinal cord injury admitted to the Neurocritical Care Unit of the University Hospital of Geneva (2022-2024).

Results

Higher fever burden increased the odds of poorer neurological recovery

OR by subgroup · 95% CI

More results

Inclusion required surgical intervention within 48 h and continuous temperature monitoring; patients with concomitant severe traumatic brain injury or inability to provide consent were excluded.

Fever episodes occurred in 79.2% of patients, representing 15.8% of monitored time.

More results

Older age was associated with reduced odds of bad outcome (OR 0.97 per year, 95% CI 0.97-0.98, p < 0.001).

Early fever burden after traumatic spinal cord injury is common and independently associated with worse association outcomes at discharge.

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Conclusion

Larger, multicenter prospective studies are warranted to validate these results.

Fever Burden and Neurological Outcome in Traumatic Spinal Cord Injury.

Fever Burden and Neurological Outcome in Traumatic Spinal Cord Injury.

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