Characteristics and prognosis of skin cancer arising from burn scars: a systematic review.

Skin cancers arising from burn scars, especially squamous cell carcinoma, demonstrate aggressive clinical behavior with significant morbidity and mortality.

Reduced latency periods and high metastatic potential highlight the importance of vigilant, long-term surveillance and radical initial treatment.

This review provides a contemporary benchmark for epidemiological understanding and supports calls for international registries, molecular diagnostics, and standardized management protocols for burn scar malignancies.