Cerebral Cryptococcoma Masquerading as High-Grade Glioma in an Immunocompetent Traveler from South America: A Diagnostic Challenge and Systematic Review.

HIV serology was negative, and CD4 count was normal.

SYSTEMATIC LITERATURE REVIEW: A systematic PubMed search identified 13 previously reported cases of cerebral cryptococcoma in immunocompetent patients.

The mean age was 56.1 years (range 40-64 years), with a male predominance (69.2%, 9/13).

The most common locations were cerebral parenchyma (38.5%, 5/13) and intraventricular (23.1%, 3/13).