Surgical outcomes following spinal fusion for cervical versus noncervical fractures in ankylosing spondylitis and DISH.
Ankylosing spondylitis fracture patients have higher mortality risk than diffuse idiopathic skeletal hyperostosis patients
Surgical outcomes following spinal fusion for cervical versus noncervical fractures in ankylosing spondylitis and DISH.
Ankylosing spondylitis (ankylosing spondylitis) and diffuse idiopathic skeletal hyperostosis (diffuse idiopathic skeletal hyperostosis) are 2 distinct spondyloarthropathies characterized by progressive spinal ankylosis.
This study aims to compare 3-month, 1-year, and 2-year outcomes following spinal fusion for cervical and noncervical fractures in patients with ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis.
This was a retrospective cohort study.
Among ankylosing spondylitis patients, the cervical group exhibited a significantly lower rate of surgical site infections (surgical site infections) at 3 months (RR 0.44, p = .016), reduced thromboembolic events (RR 0.53, p = .03) at 2 years compared with ankylosing spondylitis patients with a noncervical fractures fracture.
For both ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis patients, cervical fractures were significantly associated with increased risk of spinal cord injury at all time points.
Instrumentation failure was more common in ankylosing spondylitis patients at 1 year (RR 2.27, p = .018) and 2 years (RR 1.93, p = .032).
Cervical fractures in both ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis patients showed a higher risk of SCI compared to noncervical fractures, likely secondary to the narrowing of the canal within this region.
Overall, ankylosing spondylitis patients had higher rates of mortality, instrumentation failure, and wound complications compared to those with diffuse idiopathic skeletal hyperostosis, while diffuse idiopathic skeletal hyperostosis patients had higher rates of pseudoarthrosis.